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          Metabolic Impact of High Fructose Corn Syrup Restriction in Obese Children

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          44985148 - illustration of an obese man eating his dinner in front of the tv

          Food restriction did not induce weight loss or a decrease in insulin resistance in school-age children with obesity, says a new research. Researchers examined 54 children of age 6 to 11 with obesity to determine the impact of high fructose corn syrup restriction on serum glucose, insulin, lipids, leptin, and overall liver health. They were limited to <20 g/day consumption of high fructose corn syrup for 6 weeks.

           

          Overall, 80% children adhered to the study program, reporting a decrease in high fructose corn syrup consumption from 110±38.6 g/day to 11.4±12.0 g/day.  Significant decreases in caloric intake (2384±568 kcal/day to 1757±387 kcal/day) and carbohydrate consumption (302±80.4 to 203±56.0 g/day) were also noted. There were no changes in BMI or diastolic BP and markers of insulin resistance remained the same. Although 73.1% participants presented with fatty liver at the beginning of the study, a decrease in liver steatosis was noted following intervention.

          There was fructose restriction associated with diminution of triglyceride levels and an important diminution of liver steatosis. The results did not show any changes of body weight or insulin resistance that may be explained by adaptive changes in metabolic expenditure.

          Since study involved the pediatric population, findings may not be generalizable to entire population.

          Ref: http://www.endocrinologyadvisor.com/pediatric-endocrinology/triglycerides-decrease-with-high-fructose-food-restriction-in-children/article/684263/


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